Mike Bowl is an Action on Hearing Loss-funded researcher at the MRC (Medical Research Council) Mammalian Genetics Unit at Harwell in Oxfordshire. We awarded him an International Project Grant to study the role of three new genes in the development and maintenance of the inner ear.
Mike is a Senior Investigator Scientist at the Mammalian Genetics Unit, MRC Harwell. His main research interest involves the identification and study of genes required for hearing – and the molecular processes underlying hearing loss.
Mike’s team uses the Harwell Ageing Screen, the first large-scale project to specifically generate animal models of age-related human disease. Using hearing screening, he identifies animal models of early- and late-onset hearing loss, and studies them to discover new genes linked to hearing – and to uncover the processes required for normal hearing function.
You can find out more about Mike’s work on his lab webpage.
What do you see as the most exciting breakthrough(s) in hearing research in the last 10 years?
They come from our increased understanding of the genes underlying hearing loss. And they’ve been aided greatly by advances in new DNA-sequencing technologies. Having the ability to rapidly and robustly identify the genetic mutations underlying hearing loss is critical for research.
What do you want your research to achieve?
Ultimately, our increased knowledge of the genes and molecular processes required for hearing will lead to strategies to prevent hearing loss – or even restore hearing.